| Hauramopmoold | Дата: Суббота, 09.02.2013, 14:23:54 | Сообщение # 1 |
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While sinemet is the most effective medication and has the least short-term side effects, it is associated with high risks of long-term side effects, such as involuntary movements (dyskinesia). used on a long-term basis, levodopa may also cause restlessness, confusion, or abnormal movements. changes in the amount or timing of the dose will usually prevent these side effects, but most experts now recommend alternatives to sinemet, such as the dopamine agonists, and use sinemet only when the alternatives fail to provide sufficient relief.
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If you are worried about a possible overdose, i would recommend getting one of those pill boxes with the days of the week on. you can fill one up for him week at a time and you can visually keep track of the pills he is taking.
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There are dopamine agonists which mimic dopamine - stimulate a response. they bind to different dopamine receptors. one function is to raise prolactin levels. like the dopaminergics, they have a wearing off time which increases the longer one is on the medication. often they are coupled with a dopamine antagonist. these meds include parlodel, requip xl (non-ergot derived), mirapex (can cause hallucinations and compulsive behavior but excellent for pd symptoms if you can tolerate the side effects), the neupro transdermal patch which is awaiting re-approval by the fda in the us market. it has been restored to the european market following a glitch which did not impact its effectiveness. there are more but not as commonly used or not available in the us market.
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