| AEdimmisee | Дата: Понедельник, 20.05.2013, 09:35:54 | Сообщение # 1 |
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Disulfiram plus even small amounts of alcohol produces flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, copious vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, marked uneasiness, weakness, vertigo, blurred vision, and confusion. in severe reactions, there may be respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death. the intensity of the reaction may vary with each individual but is generally proportional to the amount of disulfiram and alcohol ingested. in the sensitive individual, mild reactions may occur when the blood alcohol concentration is increased to as little as 5 to 10 mg100 ml. at a concentration of 50 mg100 ml symptoms are usually fully developed, and when the concentration reaches 125 to 150 mg100 ml unconsciousness may occur.
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Disulfiram is slowly absorbed from the gastrointestinal tract and is slowly eliminated from the body. ingestion of alcohol may produce unpleasant symptoms 1 or even 2 weeks after a patient has taken his last dose of disulfiram.
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Antabuse takes up to 14 days to completely leave your system.
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